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OCeanmin. Клинические исследования продукта

OCeanmin. Клинические исследования продукта
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статья действие Mg Ca K Минера-лизация ссылки на публикацию ссылки в интернете  метаболический синдром   Deep Sea Water Modulates Blood Pressure and Exhibits Hypolipidemic Effects via the AMPK-ACC Pathway: An in Vivo Study артериальное давление 96 mg/L - - 400 mg/L Sheu MJ, Chou PY, Lin ...

OCeanmin. Клинические исследования продукта


статья
действие
Mg
Ca
K
Минера-лизация
ссылки на публикацию
ссылки в интернете
 метаболический синдром
 
Deep Sea Water Modulates Blood Pressure and Exhibits Hypolipidemic Effects via the AMPK-ACC Pathway: An
in Vivo Study
артериальное давление
96 mg/L
-
-
400 mg/L
Sheu MJ, Chou PY, Lin WH, Pan CH, Chien YC, Chung YL, Liu FC, Wu CH. Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study. Mar Drugs. 2013 Jun 17;11(6):2183-202. doi: 10.3390/md11062183. PMID: 23774889; PMCID: PMC3721228.
Effects of deep-seawater on blood lipids and pressure in high-cholesterol dietary mice
артериальное давление
999 mg/L
236 mg/L
14 mg/L
4600 mg/L
Chang M.-H., Tzang B.-S., Yang T.-Y., Hsiao Y.-C., Yang H.-C., Chen Y.-C. Effects of deep-seawater on blood lipids and pressure in high-cholesterol dietary mice. Journal of Food Biochemistry. 2011;35(1) :241–259
Drinking Deep Seawater Decreases Serum Total and Low-Density
Lipoprotein–Cholesterol in Hypercholesterolemic Subjects
холестерин
395 mg/L
6,58 mg/L
35 mg/L
1400 mg/L
Fu ZY, Yang FL, Hsu HW, Lu YF. Drinking deep seawater decreases serum total and low-density lipoprotein-cholesterol in hypercholesterolemic subjects. J Med Food. 2012 Jun;15(6):535-41. doi: 10.1089/jmf.2011.2007. Epub 2012 Mar 16. PMID: 22424458; PMCID: PMC3359629.
Deep Sea Water Modulates Blood Pressure and Exhibits Hypolipidemic Effects via the AMPK-ACC Pathway: An
in Vivo Study
гиполипидемия (холестерин)
96 mg/L
-
-
400 mg/L
Sheu MJ, Chou PY, Lin WH, Pan CH, Chien YC, Chung YL, Liu FC, Wu CH. Deep sea water modulates blood pressure and exhibits hypolipidemic effects via the AMPK-ACC pathway: an in vivo study. Mar Drugs. 2013 Jun 17;11(6):2183-202. doi: 10.3390/md11062183. PMID: 23774889; PMCID: PMC3721228.
Effect of cholesterol level in Plasma of Rats by Drinking High Magnesium Water
Made from Deep Sea Water
холестерин
200, 600, 1000 mg/L
71, 213, 355 mg/L
-
-
M. Kimura et al., "Effect of cholesterol level in plasma of rats by drinking high magnesium water made from deep sea water," MTS/IEEE Oceans 2001. An Ocean Odyssey. Conference Proceedings (IEEE Cat. No.01CH37295), 2001, pp. 1965-1966 vol.3, doi: 10.1109/OCEANS.2001.968147.
Effect of yogurt containing deep sea water on health-related serum parameters and intestinal microbiota in mice
холестерин
5,84 mg/L
10 mg/L
-
53 mg/L
Kang SM, Jhoo JW, Pak JI, Kwon IK, Lee SK, Kim GY. Effect of yogurt containing deep sea water on health-related serum parameters and intestinal microbiota in mice. J Dairy Sci. 2015 Sep;98(9):5967-73. doi: 10.3168/jds.2015-9492. Epub 2015 Jul 2. PMID: 26142849.
Modulation of Lipid Metabolism by Deep-Sea Water in Cultured Human Liver (HepG2) Cells
метаболизм липидов, холестерин
200 mg/L
70 mg/L
-
1000 mg/L
He S, Hao J, Peng W, Qiu P, Li C, Guan H. Modulation of lipid metabolism by deep-sea water in cultured human liver (HepG2) cells. Mar Biotechnol (NY). 2014 Apr;16(2):219-29. doi: 10.1007/s10126-013-9540-1. Epub 2013 Sep 24. PMID: 24057172.
Regulatory mechanism of mineral-balanced deep sea water on hypocholesterolemic effects in HepG2 hepatic cells
холестерин
835 mg/L
279 mg/L
-
4139 mg/L
Lee KS, Kwon YS, Kim S, Moon DS, Kim HJ, Nam KS. Regulatory mechanism of mineral-balanced deep sea water on hypocholesterolemic effects in HepG2 hepatic cells. Biomed Pharmacother. 2017 Feb;86:405-413. doi: 10.1016/j.biopha.2016.12.046. Epub 2016 Dec 21. PMID: 28012395.
Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation
of hepatic lipid metabolic gene expression
холестерин
83 - 400 mg/L
27 - 130 mg/L
8 - 40mg/L
400-2000mg/L
Lee KS, Chun SY, Kwon YS, Kim S, Nam KS. Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation of hepatic lipid metabolic gene expression. Mol Med Rep. 2017 May;15(5):2814-2822. doi: 10.3892/mmr.2017.6317. Epub 2017 Mar 13. PMID: 28447751.
Pharmacological Activity of Deep-Sea Water: Examination of Hyperlipemia Prevention and Medical Treatment Effect
холестерин
5,3 - 240mg/L
20-86 mg/L
2-17 mg/L
300- 1200 mg/L
Yoshioka S, Hamada A, Cui T, Yokota J, Yamamoto S, Kusunose M, Miyamura M, Kyotani S, Kaneda R, Tsutsui Y, Odani K, Odani I, Nishioka Y. Pharmacological activity of deep-sea water: examination of hyperlipemia prevention and medical treatment effect. Biol Pharm Bull. 2003 Nov;26(11):1552-9. doi: 10.1248/bpb.26.1552. PMID: 14600400.
Anti-obesity and Antidiabetic Effects of Deep Sea Water on ob/ob Mice
метаболический синдром
810 mg/L
270 mg/L
268 mg/L
-
Hwang, H.S., Kim, H.A., Lee, S.H. et al. Anti-obesity and Antidiabetic Effects of Deep Sea Water on ob/ob Mice. Mar Biotechnol 11, 531 (2009). https://doi.org/10.1007/s10126-008-9171-0
Mineral-Enriched Deep-Sea Water Modulates Lactate Metabolism via PGC-1α-Mediated
Metabolic Reprogramming
метаболический синдром
405 mg/L
134 mg/L
-
-
Ha BG, Jung SS, Jang YK, Jeon BY, Shon YH. Mineral-Enriched Deep-Sea Water Modulates Lactate Metabolism via PGC-1α-Mediated Metabolic Reprogramming. Mar Drugs. 2019 Oct 27;17(11):611. doi: 10.3390/md17110611. PMID: 31717879; PMCID: PMC6891778.
Natural Magnesium-Enriched Deep-Sea Water Improves Insulin Resistance and the Lipid Profile of
Prediabetic Adults: A Randomized, Double-Blinded
Crossover Trial
метаболический синдром
815 mg/L (Korean limit )
275mg/L
-
4000 mg/L
Ham JY, Shon YH. Natural Magnesium-Enriched Deep-Sea Water Improves Insulin Resistance and the Lipid Profile of Prediabetic Adults: A Randomized, Double-Blinded Crossover Trial. Nutrients. 2020;12(2):515. Published 2020 Feb 18. doi:10.3390/nu12020515
Deep Sea Minerals Prolong Life Span of Streptozotocin-Induced Diabetic Rats by
Compensatory Augmentation of the IGF-ISurvival Signaling and Inhibition of Apoptosis
метаболический синдром
90 mg/L
0,2 mg/L
10 mg/L
400 mg/L
Liao HE, Shibu MA, Kuo WW, Pai PY, Ho TJ, Kuo CH, Lin JY, Wen SY, Viswanadha VP, Huang CY. Deep sea minerals prolong life span of streptozotocin-induced diabetic rats by compensatory augmentation of the IGF-I-survival signaling and inhibition of apoptosis. Environ Toxicol. 2016 Jul;31(7):769-81. doi: 10.1002/tox.22086. Epub 2015 Mar 2. PMID: 25727812.
Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways
to attenuate diabetes-induced hypertrophy in rat hearts
метаболический синдром
96 mg/L
-
-
400 mg/L
Lu CH, Shen CY, Hsieh DJ, Lee CY, Chang RL, Ju DT, Pai PY, Viswanadha VP, Ou HC, Huang CY. Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways to attenuate diabetes-induced hypertrophy in rat hearts. J Appl Physiol (1985). 2019 Aug 1;127(2):356-364. doi: 10.1152/japplphysiol.00184.2019. Epub 2019 May 16. PMID: 31095463.
Inhibitory effect of deep-sea water on differentiation of 3T3-L1 adipocytes
ожирение
810-1300
270-417
268-390
4000 mg/L
Hwang HS, Kim SH, Yoo YG, Chu YS, Shon YH, Nam KS, Yun JW. Inhibitory effect of deep-sea water on differentiation of 3T3-L1 adipocytes. Mar Biotechnol (NY). 2009 Mar-Apr;11(2):161-8. doi: 10.1007/s10126-008-9131-8. Epub 2008 Jul 25. PMID: 18654820.
Desalinated underground seawater of Jeju Island (Korea) improves lipid
metabolism in mice fed diets containing high fat and increases antioxidant
potential in t-BHP treated HepG2 cells
ожирение
461 mg/L
321 mg/L
17 mg/L
-
Noh JR, Gang GT, Kim YH, Yang KJ, Lee CH, Na OS, Kim GJ, Oh WK, Lee YD. Desalinated underground seawater of Jeju Island (Korea) improves lipid metabolism in mice fed diets containing high fat and increases antioxidant potential in t-BHP treated HepG2 cells. Nutr Res Pract. 2010 Feb;4(1):3-10. doi: 10.4162/nrp.2010.4.1.3. Epub 2010 Feb 24. PMID: 20198202; PMCID: PMC2830411.
Mineral-Enriched Deep-Sea Water Modulates Lactate Metabolism via PGC-1α-Mediated
Metabolic Reprogramming
ожирение
405 mg/L
134 mg/L
-
-
Ha BG, Jung SS, Jang YK, Jeon BY, Shon YH. Mineral-Enriched Deep-Sea Water Modulates Lactate Metabolism via PGC-1α-Mediated Metabolic Reprogramming. Mar Drugs. 2019 Oct 27;17(11):611. doi: 10.3390/md17110611. PMID: 31717879; PMCID: PMC6891778.
Deep Sea Water Improves Abnormalities in Lipid Metabolism through Lipolysis and Fatty Acid
Oxidation in High-Fat Diet-Induced Obese Rats
ожирение
96 mg/L
0,4 mg/L
10 mg/L
-
Chang WT, Lu TY, Cheng MC, Lu HC, Wu MF, Hsu CL. Deep Sea Water Improves Abnormalities in Lipid Metabolism through Lipolysis and Fatty Acid Oxidation in High-Fat Diet-Induced Obese Rats. Mar Drugs. 2017 Dec 11;15(12):386. doi: 10.3390/md15120386. PMID: 29232925; PMCID: PMC5742846.
 
 
Deep-Sea Water Improves Cardiovascular Hemodynamics in Kurosawa
and Kusanagi-Hypercholesterolemic (KHC) Rabbits
сердечно сосудистая система
200 mg/L
-
-
1000 mg/L
Katsuda S, Yasukawa T, Nakagawa K, Miyake M, Yamasaki M, Katahira K, Mohri M, Shimizu T, Hazama A. Deep-sea water improves cardiovascular hemodynamics in Kurosawa and Kusanagi-Hypercholesterolemic (KHC) rabbits. Biol Pharm Bull. 2008 Jan;31(1):38-44. doi: 10.1248/bpb.31.38. PMID: 18175939.
Cardiovascular protection of deep-seawater drinking water in high-fat/cholesterol fed hamsters
сердечно сосудистая система
70-340 mg/L
15-70 mg/L
12-13 mg/L
325-1570 mg/L
Hsu CL, Chang YY, Chiu CH, Yang KT, Wang Y, Fu SG, Chen YC. Cardiovascular protection of deep-seawater drinking water in high-fat/cholesterol fed hamsters. Food Chem. 2011 Aug 1;127(3):1146-52. doi: 10.1016/j.foodchem.2011.01.116. Epub 2011 Feb 23. PMID: 25214107.
Pharmacological Activity of Deep-Sea Water: Examination of Hyperlipemia Prevention and Medical Treatment Effect
гиперлипимия
60-240 mg/L
1,8 - 20mg/L
2-17 mg/L
300-1200 mg/L
Yoshioka S, Hamada A, Cui T, Yokota J, Yamamoto S, Kusunose M, Miyamura M, Kyotani S, Kaneda R, Tsutsui Y, Odani K, Odani I, Nishioka Y. Pharmacological activity of deep-sea water: examination of hyperlipemia prevention and medical treatment effect. Biol Pharm Bull. 2003 Nov;26(11):1552-9. doi: 10.1248/bpb.26.1552. PMID: 14600400.
Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways
to attenuate diabetes-induced hypertrophy in rat hearts
сердечно сосудистая система
96 mg/L
-
-
400 mg/L
Lu CH, Shen CY, Hsieh DJ, Lee CY, Chang RL, Ju DT, Pai PY, Viswanadha VP, Ou HC, Huang CY. Deep ocean minerals inhibit IL-6 and IGFIIR hypertrophic signaling pathways to attenuate diabetes-induced hypertrophy in rat hearts. J Appl Physiol (1985). 2019 Aug 1;127(2):356-364. doi: 10.1152/japplphysiol.00184.2019. Epub 2019 May 16. PMID: 31095463.
 
 
Deep ocean mineral water accelerates recovery from physical fatigue
работоспособность/ выносливость
140 mg/L
54mg/L
115 mg/L
-
Hou CW, Tsai YS, Jean WH, Chen CY, Ivy JL, Huang CY, Kuo CH. Deep ocean mineral water accelerates recovery from physical fatigue. J Int Soc Sports Nutr. 2013 Feb 12;10(1):7. doi: 10.1186/1550-2783-10-7. PMID: 23402436; PMCID: PMC3583772.
Effect of Deep Sea Water on the Exercise-Induced Fatigue of Rats
работоспособность/ выносливость
19-113 mg/L
3-18 mg/L
0-2 mg/L
0-600 mg/L
Wang, S.-T.; Hwang, D.-F.; Chen, R.-H.; Chen, Y.-C.; Liang, C.-W.; Lin, C.-S.; and Tsai, M.-L. (2009) "Effect of deep sea water on the exercise-induced fatigue of rats," Journal of Food and Drug Analysis: Vol. 17 : Iss. 2 , Article 9.
Oral Ingestion of Deep Ocean Minerals Increases High-Intensity Intermittent Running Capacity in
Soccer Players after Short-Term Post-Exercise
Recovery: A Double-Blind, Placebo-Controlled
Crossover Trial
работоспособность/ выносливость
170 mg/L
54 mg/L
56 mg/L
-
Higgins, Matthew F et al. “Oral Ingestion of Deep Ocean Minerals Increases High-Intensity Intermittent Running Capacity in Soccer Players after Short-Term Post-Exercise Recovery: A Double-Blind, Placebo-Controlled Crossover Trial.” Marine drugs vol. 17,5 309. 24 May. 2019, doi:10.3390/md17050309
Nigari (deep seawater concentrate) enhances the treadmill exercise performance of gerbils.
работоспособность/ выносливость
96 mg/L
0,039 mg/L
10 mg/L
 
Wang ML, Chen YJ, Cheng FC. Nigari (deep seawater concentrate) enhances the treadmill exercise performance of gerbils. Biol Sport. 2014;31(1):69-72. doi:10.5604/20831862.1086735
Deep Ocean Mineral Supplementation Enhances the Cerebral Hemodynamic Response during Exercise and Decreases Inflammation Postexercise in Men at Two Age Levels
работоспособность воспаление
146 mg/L
0,2 mg/L
46 mg/L
-
Wei CY, Chen CY, Liao YH, Tsai YS, Huang CY, Chaunchaiyakul R, Higgins MF, Kuo CH. Deep Ocean Mineral Supplementation Enhances the Cerebral Hemodynamic Response during Exercise and Decreases Inflammation Postexercise in Men at Two Age Levels. Front Physiol. 2017 Dec 12;8:1016. doi: 10.3389/fphys.2017.01016. PMID: 29311955; PMCID: PMC5733072.
Deep mineral water accelerates recovery after dehydrating aerobic exercise: a randomized, double-blind, placebo-controlled crossover study
работоспособность восстановление
73 mg/L
19 mg/L
220 mg/L
-
Stasiule, Loreta et al. “Deep mineral water accelerates recovery after dehydrating aerobic exercise: a randomized, double-blind, placebo-controlled crossover study.” Journal of the International Society of Sports Nutrition vol. 11 34. 26 Jun. 2014, doi:10.1186/1550-2783-11-34
Deep Ocean Minerals Minimize Eccentric Exercise-Induced Inflammatory Response of Rat Skeletal Muscle
работоспособность
165 mg/L
16 mg/L
39 mg/L
600 mg/L
Saovieng S, Wu J, Huang CY, Kao CL, Higgins MF, Chuanchaiyakul R, Kuo CH. Deep Ocean Minerals Minimize Eccentric Exercise-Induced Inflammatory Response of Rat Skeletal Muscle. Front Physiol. 2018 Sep 28;9:1351. doi: 10.3389/fphys.2018.01351. PMID: 30323766; PMCID: PMC6172318.
Supplementation of nanofiltrated deep ocean water ameliorate
the progression of osteoporosis in ovariectomized rat via
regulating osteoblast differentiation
остеопороз
60-70 mg/L
100-300 mg/L
-
-
Supplementation of nanofiltrated deep ocean water ameliorate
the progression of osteoporosis in ovariectomized rat via
regulating osteoblast differentiation
 
 
Modulation of Lipid Metabolism by Deep-Sea Water in Cultured Human Liver (HepG2) Cells
печень
200 mg/L
70mg/L
-
1000 mg/L
He S, Hao J, Peng W, Qiu P, Li C, Guan H. Modulation of lipid metabolism by deep-sea water in cultured human liver (HepG2) cells. Mar Biotechnol (NY). 2014 Apr;16(2):219-29. doi: 10.1007/s10126-013-9540-1. Epub 2013 Sep 24. PMID: 24057172.
Alleviative effects of deep-seawater drinking water on hepatic lipid
accumulation and oxidation induced by a high-fat diet
печень
68- 330 mg/L
12-65 mg/L
13-27 mg/L
310-1500mg/L
Chen IS, Chang YY, Hsu CL, Lin HW, Chang MH, Chen JW, Chen SS, Chen YC. Alleviative effects of deep-seawater drinking water on hepatic lipid accumulation and oxidation induced by a high-fat diet. J Chin Med Assoc. 2013 Feb;76(2):95-101. doi: 10.1016/j.jcma.2012.10.008. Epub 2012 Dec 29. PMID: 23351420.
Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation
of hepatic lipid metabolic gene expression
печень
83 - 400 mg/L
27 - 130 mg/L
8 - 40mg/L
400-2000mg/L
Lee KS, Chun SY, Kwon YS, Kim S, Nam KS. Deep sea water improves hypercholesterolemia and hepatic lipid accumulation through the regulation of hepatic lipid metabolic gene expression. Mol Med Rep. 2017 May;15(5):2814-2822. doi: 10.3892/mmr.2017.6317. Epub 2017 Mar 13. PMID: 28447751.
Difference between Deep Seawater and Surface Seawater in the Preventive
Effect of Atherosclerosis
атеросклероз
240 mg/L
85mg/L
20 mg/L
1200 mg/L
Miyamura M, Yoshioka S, Hamada A, Takuma D, Yokota J, Kusunose M, Kyotani S, Kawakita H, Odani K, Tsutsui Y, Nishioka Y. Difference between deep seawater and surface seawater in the preventive effect of atherosclerosis. Biol Pharm Bull. 2004 Nov;27(11):1784-7. doi: 10.1248/bpb.27.1784. PMID: 15516723.
Reduction of Allergic Skin Responses and Serum Allergen-Specific IgE and IgE-Inducing Cytokines by Drinking Deep-Sea Water in Patients with Allergic Rhinitis
аллергия ринит
200 mg/L
70 mg/L
70 mg/L
-
Kimata, H. et al. “Reduction of Allergic Skin Responses and Serum Allergen-Specific IgE and IgE-Inducing Cytokines by Drinking Deep-Sea Water in Patients with Allergic Rhinitis.” Oto-Rhino-Laryngologia Nova 11 (2001): 302 - 303.
Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome
дерматит
200 mg/L
71 mg/L
69 mg/L
1000 mg/L
Hataguchi Y, Tai H, Nakajima H, Kimata H. Drinking deep-sea water restores mineral imbalance in atopic eczema/dermatitis syndrome. Eur J Clin Nutr. 2005 Sep;59(9):1093-6. doi: 10.1038/sj.ejcn.1602218. PMID: 16015263.
Deep-Sea Water Containing Selenium Provides Intestinal Protection against Duodenal Ulcers through the
Upregulation of Bcl-2 and Thioredoxin Reductase 1
кишечник
225-448mg/L
1-2mg/L
67-133 mg/L
600- 1200 mg/L
Yang CC, Yao CA, Lin YR, Yang JC, Chien CT. Deep-sea water containing selenium provides intestinal protection against duodenal ulcers through the upregulation of Bcl-2 and thioredoxin reductase 1. PLoS One. 2014 Jul 1;9(7):e96006. doi: 10.1371/journal.pone.0096006. PMID: 24984066; PMCID: PMC4077573.
Antibacterial Activities of Refined Deep Seawater on Helicobacter pylori
кишечник
1,5mg/L - 240mg/L
9,7mg/L -350mg/L
-
-
Kawada, Masahiko. (2013). Antibacterial Activities of Refined Deep Seawater on Helicobacter pylori. Journal of Medical Microbiology & Diagnosis. 01. 10.4172/2161-0703.S1-002.
Effect of yogurt containing deep sea water on health-related serum parameters and intestinal microbiota in mice
кишечник
5,84 mg/L
10 mg/L
-
53 mg/L
Kang SM, Jhoo JW, Pak JI, Kwon IK, Lee SK, Kim GY. Effect of yogurt containing deep sea water on health-related serum parameters and intestinal microbiota in mice. J Dairy Sci. 2015 Sep;98(9):5967-73. doi: 10.3168/jds.2015-9492. Epub 2015 Jul 2. PMID: 26142849.
Drinking Refined Deep-Sea Water Improves the Gut Ecosystem with Beneficial Effects on Intestinal Health
in Humans: A Randomized Double-Blind
Controlled Trial
кишечник
200 mg/L
71 mg/L
69 mg/L
1000 mg/L
Takeuchi H, Higuchi K, Yoshikane Y, Takagi R, Tokuhiro S, Takenaka K, Oboshi W, Kimura A, Islam JM, Kaneko A, Sato S, Ishizuka S. Drinking Refined Deep-Sea Water Improves the Gut Ecosystem with Beneficial Effects on Intestinal Health in Humans: A Randomized Double-Blind Controlled Trial. Nutrients. 2020 Aug 31;12(9):2646. doi: 10.3390/nu12092646. PMID: 32878045; PMCID: PMC7551512.
Delay of Cataract Development in the Shumiya Cataract Rat by Water Containing
Enhanced Concentrations of Magnesium
and Calcium
глаза
200 - 1000 mg/L
71 - 335 mg/L
69-345 mg/L
-
Nagai N, Ito Y. Delay of cataract development in the Shumiya cataract rat by water containing enhanced concentrations of magnesium and calcium. Curr Eye Res. 2007 May;32(5):439-45. doi: 10.1080/02713680701329339. PMID: 17514529.
Deep Sea Water Prevents Balloon Angioplasty-Induced
Hyperplasia through MMP-2: An In Vitro and In Vivo
Study
гиперлазия
96 mg/L
-
-
400 mg/L
Li PC, Pan CH, Sheu MJ, Wu CC, Ma WF, Wu CH. Deep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: an in vitro and in vivo study. PLoS One. 2014 May 13;9(5):e96927. doi: 10.1371/journal.pone.0096927. PMID: 24824358; PMCID: PMC4019650.

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